is , while it's Molecular Formula is C17H16FN3O2S . C4H4O4. Vonoprazan Fumarate is a novel potassium-?competitive acid blocker for the treatment of acid-?related diseases.

What is the CAS number for ?

The CAS number of is 1260141-27-2.

What is (1260141-27-2) used for?

Vonoprazan is a selective, reversible, and potassium-competitive proton pump inhibitor that inhibits gastric H+/K+ ATPase (IC50 = 17 nM) but does not inhibit porcine Na+/K+ ATPase activity when used at a concentration of 10 μM. It maintains its inhibitory effect in both weakly acidic (pH 6.5) and neutral (pH 7.5) conditions with IC50 values of 19 and 28 nM, respectively. In vivo, vonoprazan (1, 2, and 4 mg/kg) inhibits histamine-stimulated acid secretion in a dose-dependent manner in rats, with complete inhibition when administered at a dose of 4 mg/kg. It also inhibits acid secretion for more than 48 hours in dogs when administered at doses ranging from 0.1 to 1 mg/kg.

is , while it's Molecular Formula is C17H16FN3O2S . C4H4O4. Vonoprazan Fumarate is a novel potassium-?competitive acid blocker for the treatment of acid-?related diseases.

What is the CAS number for ?

The CAS number of is 1260141-27-2.

What is (1260141-27-2) used for?

Vonoprazan is a selective, reversible, and potassium-competitive proton pump inhibitor that inhibits gastric H+/K+ ATPase (IC50 = 17 nM) but does not inhibit porcine Na+/K+ ATPase activity when used at a concentration of 10 μM. It maintains its inhibitory effect in both weakly acidic (pH 6.5) and neutral (pH 7.5) conditions with IC50 values of 19 and 28 nM, respectively. In vivo, vonoprazan (1, 2, and 4 mg/kg) inhibits histamine-stimulated acid secretion in a dose-dependent manner in rats, with complete inhibition when administered at a dose of 4 mg/kg. It also inhibits acid secretion for more than 48 hours in dogs when administered at doses ranging from 0.1 to 1 mg/kg.

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Органическая химия
Химические реагенты
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Аналитическая химия
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Биохимическая инженерия
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1260141-27-2

английское имя：
Брутто-формула：C₁₇H₁₆FN₃O₂S^.C₄H₄O₄
Степень чистоты：99%
Молярная масса：461.46

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CAS номер： 1260141-27-2

Брутто-формула： C₁₇H₁₆FN₃O₂S^.C₄H₄O₄

также известно как . представлено символом C17H16FN3O2S^.C4H4O4, который состоит из 21 атомов Углерод,20 атомов Водород,1 атома Фтор,3 атомов Азот и 6 атомов Кислород..

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