82834-12-6

  • Product Name:N-[1-(S)-Ethoxycarbonylbutyl]-(S)-alanine
  • Molecular Formula:C10H19NO4
  • Purity:99%
  • Molecular Weight:217.265
Inquiry

Product Details;

CasNo: 82834-12-6

Molecular Formula: C10H19NO4

Appearance: white or yellowish crystalline powder

Wholesale Factory Supply High Purity N-[1-(S)-Ethoxycarbonylbutyl]-(S)-alanine 82834-12-6 with Cheapest Price

  • Molecular Formula:C10H19NO4
  • Molecular Weight:217.265
  • Appearance/Colour:white or yellowish crystalline powder 
  • Vapor Pressure:0mmHg at 25°C 
  • Melting Point:145-150 °C 
  • Refractive Index:1.461 
  • Boiling Point:324.1 °C at 760 mmHg 
  • PKA:2.15±0.10(Predicted) 
  • Flash Point:149.8 °C 
  • PSA:75.63000 
  • Density:1.079 g/cm3 
  • LogP:1.17180 

N-[(S)-1-Carbethoxy-1-butyl]-(S)-alanine (Cas 82834-12-6) Usage

Chemical Properties

Off-White Solid

Uses

Perindopril intermediate. N-[(S)-1-Carbethoxy-1-butyl]-(S)-alanine is for research and development purpose only which may not be used directly as drugs, food, cosmetics or for any other non-R&D purpose.

Consumer Uses

ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

InChI:InChI=1/C10H19NO4/c1-4-6-8(10(14)15-5-2)11-7(3)9(12)13/h7-8,11H,4-6H2,1-3H3,(H,12,13)/t7-,8-/m0/s1

82834-12-6 Relevant articles

[2,3]-sigmatropic rearrangement of allylic selenimides: Strategy for the synthesis of peptides, peptidomimetics, and N-aryl vinyl glycines

Armstrong, Alan,Emmerson, Daniel P. G.,Milner, Harry J.,Sheppard, Robert J.

, p. 3895 - 3907 (2014/05/20)

The scope of the NCS-mediated amination/...

NOVEL METHOD FOR PREPARATION OF CRYSTALLINE PERINDOPRIL ERBUMINE

-

Page/Page column 45; 46, (2010/02/11)

A process for preparation of crystalline...

82834-12-6 Process route

N-<1(S)-(ethoxycarbonyl)butyl>-L-alanine benzyl ester
112243-70-6

N-<1(S)-(ethoxycarbonyl)butyl>-L-alanine benzyl ester

N-<1(S)-(ethoxycarbonyl)butyl>-L-alanine
82834-12-6

N-<1(S)-(ethoxycarbonyl)butyl>-L-alanine

Conditions
Conditions Yield
With hydrogen; palladium on activated charcoal; In ethanol; for 0.5h; under 2280 Torr;
86%
With hydrogen; palladium 10% on activated carbon; In ethanol; for 1.5 - 2h; under 2068.65 - 2327.23 Torr; Product distribution / selectivity;
 
With hydrogen; palladium 10% on activated carbon; In ethanol; for 1.5 - 2h; under 2068.65 - 2327.23 Torr; Product distribution / selectivity;
 
With hydrogen; palladium 10% on activated carbon; In ethanol; for 1.5 - 2h; under 2068.65 - 2327.23 Torr;
 
sodium pyruvate
113-24-6

sodium pyruvate

(S)-norvaline ethyl ester hydrochloride
40918-51-2

(S)-norvaline ethyl ester hydrochloride

N-<1(S)-(ethoxycarbonyl)butyl>-L-alanine
82834-12-6

N-<1(S)-(ethoxycarbonyl)butyl>-L-alanine

Conditions
Conditions Yield
With hydrogen; palladium-carbon; In tetrahydrofuran; ethanol; at 40 ℃; for 40.5h; under 22502.3 Torr; Product distribution / selectivity; Heating / reflux;
 
With hydrogen; palladium-carbon; In tetrahydrofuran; ethanol; water; at 40 ℃; for 10.5h; under 22502.3 Torr; Product distribution / selectivity; Heating / reflux;
 

82834-12-6 Upstream products

  • 112243-70-6
    112243-70-6

    N-<1(S)-(ethoxycarbonyl)butyl>-L-alanine benzyl ester

  • 88945-70-4
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    ethyl 2-hydroxy-n-valerate

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    109684-05-1

    ethyl 2-([(trifluoromethyl)sulphonyl]oxy)pentanoate

  • 113-24-6
    113-24-6

    sodium pyruvate

82834-12-6 Downstream products

  • 866430-96-8
    866430-96-8

    (2S,3aS,7aS)-1-{2-[1-ethoxycarbonyl-(S)-butylamino]-(S)-propionyl}-octahydroindole-2-carboxylic acid p-nitrobenzylic ester

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    109785-12-8

    (S)-5-tert-Butyl-3-[(S)-2-((S)-1-ethoxycarbonyl-butylamino)-propionyl]-2,3-dihydro-[1,3,4]thiadiazole-2-carboxylic acid benzyl ester

  • 122454-52-8
    122454-52-8

    (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid benzyl ester

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    82834-16-0

    Perindopril