1077-28-7
- Product Name：Alpha lipoic acid
- Molecular Formula：C8H14O2S2
- Purity：99%
- Molecular Weight：206.32
Product Details;
CasNo： 1077-28-7
Molecular Formula： C8H14O2S2
Appearance： light yellow to yellow powder
Buy Quality Alpha lipoic acid 1077-28-7, Export with Cheapest Price
- Molecular Formula:C8H14O2S2
- Molecular Weight:206.32
- Appearance/Colour:light yellow to yellow powder
- Melting Point:60-62 °C
- Refractive Index:1.5200 (estimate)
- Boiling Point:362.5 °C at 760 mmHg
- PKA:4.75±0.10(Predicted)
- Flash Point:173 °C
- PSA：87.90000
- Density:1.218 g/cm3
- LogP:2.78510
Alpha lipoic acid (Cas 1077-28-7) Usage
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Description |
Alpha-lipoic acid is a medication used to manage and treat chronic diseases associated with oxidative stress, such as diabetic neuropathy, and slow down the onset of metabolic syndrome by acting as an antioxidant. |
| Uses | Alpha-lipoic acid helps lower blood sugar levels. Its ability to kill free radicals may help people with diabetic peripheral neuropathy, who have pain, burning, itching, tingling, and numbness in arms and legs from nerve damage. |
1077-28-7 Relevant articles
Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential
Kate Petersen Shay a, Régis F. Moreau a, Eric J. Smith a b, Anthony R. Smith a, Tory M. Hagen a b
, Biochimica et Biophysica Acta (BBA) - General Subjects Volume 1790, Issue 10, October 2009, Pages 1149-1160
Alpha-lipoic acid (LA) has become a common ingredient in multivitamin formulas, anti-aging supplements, and even pet food. It is well-defined as a therapy for preventing diabetic polyneuropathies, and scavenges free radicals, chelates metals, and restores intracellular glutathione levels which otherwise decline with age.
Catalytic Oxidation of Dithiols by a Semisynthetic Enzyme
Stewart, Kent D.,Radziejewski, Czestaw,Kaiser, E. T.
, p. 3480 - 3483 (1986)
The semisynthetic enzyme flavopapain (1C...
A Reagent for Reduction of Disulfide Bonds in Proteins That Reduces Disulfide Bonds Faster Than Does Dithiothreitol
Singh, Rajeeva,Whitesides, George M.
, p. 2332 - 2337 (1991)
We have synthesized a new reagent - N,N'...
Equilibrium Constants for Thiol-Disulfide Interchange Reactions: A Coherent, Corrected Set
Lees, Watson J.,Whitesides, George M.
, p. 642 - 647 (1993)
Equilibrium constants (Keq) for the thio...
Oxidation-triggered aggregation of gold nanoparticles for naked-eye detection of hydrogen peroxide
Wu, Shaojue,Tan, Si Yu,Ang, Chung Yen,Luo, Zhong,Zhao, Yanli
, p. 3508 - 3511 (2016/03/04)
Naked-eye detection of H2O2 was realized...
Chirality induction and chiron approaches to enantioselective total synthesis of α-lipoic acid
Chavan, Subhash P.,Pawar, Kailash P.,Praveen, Ch.,Patil, Niteen B.
, p. 4213 - 4218 (2015/06/02)
Abstract An efficient, short and conveni...
1077-28-7 Process route
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- 1082892-39-4
(E)-4-(3,5-diacetoxystyryl)phenyl-5-(1,2-dithiolan-3-yl)pentanoate
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- 71-50-1
acetate
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![(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol](/upload/2023/8/58d7ad17-7e6f-47c6-bf9b-059406a80434.png)
- 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
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lipoate
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- 1077-28-7,62-46-4
Thioctic acid
| Conditions | Yield |
|---|---|
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With water; Stratum corneum; enzyme extract of; In acetonitrile; at 35 ℃; for 48h; Product distribution / selectivity; Enzymatic reaction; Darkness;
|
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- 41324-23-6
methyl 6-oxooct-7-enoate
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- 1077-28-7,62-46-4
Thioctic acid
| Conditions | Yield |
|---|---|
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With cobalt polysulfide; hydrogen; sulfur; acetic acid; at 175 ℃; under 58840.6 - 73550.8 Torr; anschl. mit wss. NaOH und anschl. Behandeln der mit Eisen(III)-chlorid versetzten wss. Loesung mit Sauerstoff;
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Multi-step reaction with 2 steps
2: acetic acid; hydrogen; cobalt polysulfide; sulfur / 175 °C / 58840.6 - 73550.8 Torr / anschl. mit wss. NaOH und anschl. Behandeln der mit Eisen(III)-chlorid versetzten wss. Lsg. mit Sauerstoff
With cobalt polysulfide; hydrogen; sulfur; acetic acid;
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|
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Multi-step reaction with 2 steps
1: NaH
2: acetic acid; hydrogen; cobalt polysulfide; sulfur / 175 °C / 58840.6 - 73550.8 Torr / anschl. mit wss. NaOH und Behandeln der mit Eisen(III)-chlorid versetzten wss. Loesung mit Sauerstoff
With cobalt polysulfide; hydrogen; sodium hydride; sulfur; acetic acid;
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1077-28-7 Upstream products
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114113-97-2
5-((7R,10S)-7-Isopropyl-10-methyl-1-oxo-1λ4,5-dithia-spiro[5.5]undec-2-yl)-pentanoic acid
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88818-23-9
(S)-methyl lipoate
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46236-19-5
1,2-dithiolane-3-pentanoic acid methyl ester
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98441-85-1
α-dihydrolipoic acid
1077-28-7 Downstream products
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119365-69-4
(R)-6,8-dimercaptooctanoic acid
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1365619-36-8
2-(2-(4-N-(4-(1,2-dithiolane)pentanecarboxy)aminophenyl))ethylamino-N(6)-(2,2-diphenylethyl)adenosine-5'-N-ethylcarboxamide
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1365619-29-9
2-(2-(4-N-(4-(1,2-dithiolane)pentanecarboxy)aminophenyl))ethylamino-2',3'-isopropylideneadenosine-5'-N-ethylcarboxamide
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1426536-12-0
C21H31NO2S2
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