64248-62-0
- Product Name：3,4-Difluorobenzonitrile
- Molecular Formula：C7H3F2N
- Purity：99%
- Molecular Weight：139.104
Product Details;
CasNo： 64248-62-0
Molecular Formula： C7H3F2N
Appearance： white to light yellow crystal powder
Buy High Grade Reliable Quality 3,4-Difluorobenzonitrile 64248-62-0 with Low Price
- Molecular Formula:C7H3F2N
- Molecular Weight:139.104
- Appearance/Colour:white to light yellow crystal powder
- Vapor Pressure:0.574mmHg at 25°C
- Melting Point:52-54 °C(lit.)
- Refractive Index:1.486
- Boiling Point:189.3 °C at 760 mmHg
- Flash Point:69.444 °C
- PSA：23.79000
- Density:1.26 g/cm3
- LogP:1.83648
3,4-Difluorobenzonitrile(Cas 64248-62-0) Usage
|
Chemical Properties |
white to light yellow crystal powder |
|
Uses |
3,4-Difluorobenzonitrile has been used in the preparation of:fluorophenoxy herbicidesfluorine substituted benzyl amides |
|
Preparation |
The preparation of?3,4-Difluorobenzonitrile is as follows:To the dry reactor was added 289.6 kg (1.843 kmoles) of 3,4-difluorobenzamide and 800 kg of dichloroethane solution, 241.2 kg (2.02 kmoles) of dichlorosulfoxide and catalyst DMF I.5 And the reaction was carried out at 50 ° C for 5 hours with stirring. After the reaction was complete, the reaction solution was poured into ice water with stirring and the mixture was separated to obtain a crude product having a qualitative content of 96% of 3,4-difluorobenzonitrile 259.1 kg (1.788 kmoles) in 97% yield. The crude product was distilled to give a qualitative content of 99% of 3,4,8-difluorobenzonitrile 248.6 kg (1.77 kmoles) and a distillation yield of 99%. |
InChI:InChI=1/C7H3F2N/c8-6-2-1-5(4-10)3-7(6)9/h1-3H
64248-62-0 Relevant articles
One pot synthesis of aryl nitriles from aromatic aldehydes in a water environment
Chen, Qingqing,Han, Hongwei,Lin, Hongyan,Ma, Xiaopeng,Qi, Jinliang,Wang, Xiaoming,Yang, Yonghua,Zhou, Ziling
, p. 24232 - 24237 (2021/07/29)
In this study, we found a green method t...
Iodine Promoted Conversion of Esters to Nitriles and Ketones under Metal-Free Conditions
Xiao, Jing,Guo, Fengzhe,Li, Yinfeng,Li, Fangshao,Li, Qiang,Tang, Zi-Long
, p. 2028 - 2035 (2021/02/03)
We report a novel strategy to prepare va...
A kind of boron-containing compounds and their use in catalytic fluorination reaction (by machine translation)
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Paragraph 0030-0033; 0046-0049, (2019/05/28)
The invention relates to the field of fi...
64248-62-0 Process route
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- 110888-15-8
4-chloro-3-fluorobenzonitrile
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- 1099597-97-3
2-chloro-3-fluorobenzotrifluoride
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- 64248-59-5
1,2-difluoro-3-(trifluoromethyl)benzene
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- 64248-62-0
3,4-Difluorobenzonitrile
| Conditions | Yield |
|---|---|
|
With potassium fluoride; 18-crown-6 ether; In water; toluene; at 230 - 250 ℃; for 7h; Overall yield = 94 %; Inert atmosphere;
|
98.8% 85% |
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- 939-80-0
4-chloro-3-nitrobenzonitrile
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- 3272-08-0
4-hydroxy-3-nitrobenzonitrile
-
- 1009-35-4
4-fluoro-3-nitrobenzonitrile
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- 64248-62-0
3,4-Difluorobenzonitrile
| Conditions | Yield |
|---|---|
|
With biphenyl; tetramethylammonium fluoride; In N,N-dimethyl acetamide; at 80 ℃; for 0.166667h;
|
11% 29% 5% |
64248-62-0 Upstream products
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939-80-0
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-
455-86-7
3,4-Difluorobenzoic acid
-
6574-99-8
3,4-dichloro-benzonitrile
-
85118-04-3
(3,4-difluoro-phenyl)-amide
64248-62-0 Downstream products
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331-62-4
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160658-69-5
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214483-59-7
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-
448235-56-1
2-benzyl-6-cyano-2H-4,9-dioxa-2-aza-cyclopenta[b]naphthalene-1,3-dicarboxylic acid dimethyl ester
Relevant Products
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1,2,3-Trifluoro-4-nitrobenzeneCAS：771-69-7
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