1493-27-2

  • Product Name:2-Flouronitrobenzene
  • Molecular Formula:C6H4FNO2
  • Purity:99%
  • Molecular Weight:141.102
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Product Details;

CasNo: 1493-27-2

Molecular Formula: C6H4FNO2

Appearance: clear yellow to brownish liquid

Chinese Manufacturer Supply 1493-27-2, Factory Sells 2-Flouronitrobenzene Low Price

  • Molecular Formula:C6H4FNO2
  • Molecular Weight:141.102
  • Appearance/Colour:clear yellow to brownish liquid 
  • Vapor Pressure:0.000154mmHg at 25°C 
  • Melting Point:-9 - -6 °C(lit.) 
  • Refractive Index:n20/D 1.532(lit.)  
  • Boiling Point:228.863 °C at 760 mmHg 
  • Flash Point:94.444 °C 
  • PSA:45.82000 
  • Density:1.338 g/cm3 
  • LogP:2.25710 

1-Fluoro-2-nitrobenzene(Cas 1493-27-2) Usage

Chemical Properties

clear yellow to brownish liqui

Uses

o-Nitrofluorobenzene is an intermediate in the synthetic preparations of various pharmaceutical goods.

Synthesis Reference(s)

Tetrahedron, 52, p. 23, 1996 DOI: 10.1016/0040-4020(95)00867-8Tetrahedron Letters, 26, p. 2233, 1985 DOI: 10.1016/S0040-4039(00)98970-6

InChI:InChI=1/C7H8BFO3/c1-12-7-3-2-5(8(10)11)4-6(7)9/h2-4,10-11H,1H3

1493-27-2 Relevant articles

Method for synthesizing nitro (hetero) aromatic hydrocarbon

-

Paragraph 0082-0084; 0097-0099, (2022/04/08)

The invention discloses a method for syn...

Nitration of aromatics with dinitrogen pentoxide in a liquefied 1,1,1,2-tetrafluoroethane medium

Fauziev, Ruslan V.,Kharchenko, Alexandr K.,Kuchurov, Ilya V.,Zharkov, Mikhail N.,Zlotin, Sergei G.

, p. 25841 - 25847 (2021/08/09)

Regardless of the sustainable developmen...

Ipso Nitration of Aryl Boronic Acids Using Fuming Nitric Acid

Baucom, Kyle D.,Brown, Derek B.,Caille, Seb,Murray, James I.,Quasdorf, Kyle,Silva Elipe, Maria V.

supporting information, (2021/06/30)

The ipso nitration of aryl boronic acid ...

Radical Decarboxylative Carbometalation of Benzoic Acids: A Solution to Aromatic Decarboxylative Fluorination

Xu, Peng,López-Rojas, Priscila,Ritter, Tobias

supporting information, p. 5349 - 5354 (2021/05/05)

Abundant aromatic carboxylic acids exist...

1493-27-2 Process route

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Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: 3-chloro-benzenecarboperoxoic acid / 16 h / 20 °C / Sealed tube
2: sodium nitrite; sodium hydrogencarbonate / dichloromethane; water / 3 h / 60 °C / Sealed tube
With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; sodium nitrite; In dichloromethane; water;
 
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Conditions
Conditions Yield
With xenon difluoride; boron trifluoride diethyl etherate; at 0 - 25 ℃; Reagent/catalyst; Cooling with ice;
0.05 mmol
0.16 mmol
0.01 mmol
0.016 mmol
0.001 mmol

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