446-35-5
- Product Name：2,4-Difluoronitrobenzene
- Molecular Formula：C6H3F2NO2
- Purity：99%
- Molecular Weight：159.092
Product Details;
CasNo： 446-35-5
Molecular Formula： C6H3F2NO2
Appearance： yellow liquid
Top Purity 99% Buy Quality 2,4-Difluoronitrobenzene 446-35-5 Cheap Price
- Molecular Formula:C6H3F2NO2
- Molecular Weight:159.092
- Appearance/Colour:yellow liquid
- Vapor Pressure:0.331mmHg at 25°C
- Melting Point:9-10 °C(lit.)
- Refractive Index:n20/D 1.511(lit.)
- Boiling Point:207 °C at 760 mmHg
- Flash Point:90.6 °C
- PSA：45.82000
- Density:1.45 g/cm3
- LogP:2.39620
2,4-Difluoronitrobenzene(Cas 446-35-5) Usage
|
Synthesis |
KF with n-Hexadecyltrimethylammonium bromide as the PTC has been shown recently to work in dimethylformamide (DMF), important owing to the low cost16 of DMF. |
|
Chemical Properties |
yellow liquid |
|
Uses |
2,4-Difluoronitrobenzene has been used in the synthesis of: 2,4-difluoro-5-nitrobenzenesulfonic acid via sulfonation reaction; (±)-horsfiline; resin-bound 2-arylaminobenzimidazoles.2,?4-?Difluoronitrobenzene is a reactant in the preparation of 4-?thiazolidinone derivatives as antimicrobial agents. |
|
General Description |
Nucleophilic aromatic substitution of 2,4-difluoronitrobenzene with morpholine has been investigated using flow reactor with simulated moving bed (SMB) chromatography module. |
446-35-5 Relevant articles
Inexpensive, Active KF for Nucleophilic Aromatic Displacement Reactions
Smyth, Timothy P.,Carey, Aedin,Hodnett, B. K.
, p. 6363 - 6376 (1995)
The simple, and inexpensive process, of ...
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Paragraph 0201-0205; 0219-0224, (2020/01/25)
The invention relates to a novel method ...
446-35-5 Process route
-
- 148854-10-8
(2,4-difluorophenyl)trimethylsilane
-
- 372-18-9
1,3-Difluorobenzene
-
- 446-35-5
2,4-Difluoronitrobenzene
-
- 367-82-8
3-Fluoro-4,6-dinitrophenol
| Conditions | Yield |
|---|---|
|
With water; nitric acid; acetic anhydride; at 45 ℃; for 22h;
|
2.3% 32.7% 6.8% |
-
- 133117-48-3
1,3-difluoro-2-trimethylsilylbenzene
-
- 372-18-9
1,3-Difluorobenzene
-
- 19064-24-5
2,6-difluoro-1-nitrobenzene
-
- 446-35-5
2,4-Difluoronitrobenzene
-
- 186315-85-5
1,3-difluoro-4-nitro-2-(trimethylsilyl)benzene
| Conditions | Yield |
|---|---|
|
With water; nitric acid; acetic anhydride; at 65 ℃; for 24h;
|
13.4% 11.7% 2.6% |
446-35-5 Upstream products
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611-06-3
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nitrobenzene
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148854-10-8
(2,4-difluorophenyl)trimethylsilane
446-35-5 Downstream products
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327-92-4
1,5-difluoro-2,4-dinitrobenzene
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