
82419-35-0
- Product Name:Ofloxacin Q Acid
- Molecular Formula:C13H9F2NO4
- Purity:99%
- Molecular Weight:281.216
Product Details;
CasNo: 82419-35-0
Molecular Formula: C13H9F2NO4
Appearance: grey-yellow powder
Wholesale Factory Supply Ofloxacin Q Acid 82419-35-0 Cheap Price
- Molecular Formula:C13H9F2NO4
- Molecular Weight:281.216
- Appearance/Colour:grey-yellow powder
- Vapor Pressure:3.14E-09mmHg at 25°C
- Melting Point:320-322 °C(lit.)
- Boiling Point:459.2 °C at 760 mmHg
- PKA:4.87±0.40(Predicted)
- Flash Point:231.5 °C
- PSA:68.53000
- Density:1.61 g/cm3
- LogP:1.93130
Oxygen-fluorine acid(Cas 82419-35-0) Usage
Chemical Properties |
Grey-Yellow Powder |
Uses |
Ofloxacin intermediate |
General Description |
(S)-(-)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid may be used in the preparation of the following:kynurenine aminotransferase II (KAT II) inhibitor, [(S)-(-)-9-(4-aminopiperazine-1-yl)-8-fluoro-3-methyl-6-oxo-2,3,5,6-tetrahydro-4H-1-oxa-3a-aza-phenalene-5-carboxylic acid]fused-ring derivativesN-desmethyllevofloxacin |
InChI:InChI=1/C13H9F2NO4/c1-5-4-20-12-9(15)8(14)2-6-10(12)16(5)3-7(11(6)17)13(18)19/h2-3,5H,4H2,1H3,(H,18,19)/p-1/t5-/m1/s1
82419-35-0 Relevant articles
Ofloxacin preparation method (by machine translation)
-
Paragraph 0014; 0043; 0044, (2016/10/09)
The invention provides a preparation met...
Baylis-Hillman route to several quinolone antibiotic intermediates
Hong, Wan Pyo,Lee, Kee-Jung
, p. 963 - 968 (2007/10/03)
Treatment of methyl propiolate and 2,4,5...
Novel oxazolidinone-quinolone hybrid antimicrobials
Gordeev, Mikhail F.,Hackbarth, Corinne,Barbachyn, Michael R.,Banitt, Lee S.,Gage, James R.,Luehr, Gary W.,Gomez, Marcela,Trias, Joaquim,Morin, Sara E.,Zurenko, Gary E.,Parker, Christian N.,Evans, Jonathan M.,White, Richard J.,Patel, Dinesh V.
, p. 4213 - 4216 (2007/10/03)
Antimicrobial compounds incorporating ox...
Method for the preparation of pyrido benzoxazine derivatives
-
, (2008/06/13)
There is disclosed a method for the prep...
82419-35-0 Process route
-
- 178233-30-2
ethyl 2-(2-nitro-3,4,5-trifluoro) benzoyl-3-(1-t-butyldimethylsilyloxyprop-2-ylamino) acrylate

-
- 429-41-4
tetrabutyl ammonium fluoride

-
- 82419-35-0
9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]-benzoxazine-6-carboxylic acid
Conditions | Yield |
---|---|
With hydrogenchloride; potassium hydroxide; In tetrahydrofuran; ethanol; chloroform; water;
|
86% |
-
- 82419-34-9
ethyl 9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylate

-
- 82419-35-0
9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]-benzoxazine-6-carboxylic acid
Conditions | Yield |
---|---|
With hydrogenchloride; In acetic acid; for 3h; Heating;
|
94% |
With hydrogenchloride; acetic acid;
|
|
With sulfuric acid; acetic acid; In water; for 4h; Time; Reflux;
|
82419-35-0 Upstream products
-
82419-34-9
ethyl 9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylate
-
107359-16-0
ethyl 6,7,8-trifluoro-1,4-dihydro-1-(1-hydroxyprop-2-yl)-4-oxoquinoline-3-carboxylate
-
86760-99-8
diethyl [(-)-7,8-difluoro-3-methyl-2,3-dihydro-4H-[1,4]benzoxazin-4-yl]methylenemalonate
-
115551-33-2
2-hydroxy 3,4-difluoro aniline
82419-35-0 Downstream products
-
82419-52-1
N-Demethylofloxacin
-
82419-36-1
ofloxacin
-
124338-73-4
9-(4-Ethyl-piperazin-1-yl)-8-fluoro-3-methyl-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid
-
82419-59-8
8-Fluoro-3-methyl-9-(4-methyl-[1,4]diazepan-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid
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