What is the 4-Fluorobenzylamine?

4-Fluorobenzylamine is Colorless to light yellow liquid, while it's Molecular Formula is C7H8FN. Colorless to light yellow liquid 4-Fluorobenzylamine is used as a potassium channel blocking agent. It is used in the synthesis of new tris-iron(III) chelates of 3-hydroxy-4-pyridinone ligands. It reacts with the α- and γ-carboxyl groups of folic acid to yield 18F-labeled folate2. It is an important building block for the synthesis of 18F-labeled compounds.

What is the CAS number for 4-Fluorobenzylamine?

The CAS number of 4-Fluorobenzylamine is 140-75-0.

What is the 4-Fluorobenzylamine?

4-Fluorobenzylamine is Colorless to light yellow liquid, while it's Molecular Formula is C7H8FN. Colorless to light yellow liquid 4-Fluorobenzylamine is used as a potassium channel blocking agent. It is used in the synthesis of new tris-iron(III) chelates of 3-hydroxy-4-pyridinone ligands. It reacts with the α- and γ-carboxyl groups of folic acid to yield 18F-labeled folate2. It is an important building block for the synthesis of 18F-labeled compounds.

What is the CAS number for 4-Fluorobenzylamine?

The CAS number of 4-Fluorobenzylamine is 140-75-0.

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140-75-0

Product Name：4-fluorobenzylamine
Molecular Formula：C₇H₈FN
Purity：99%
Molecular Weight：125.146

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Product Details;

CasNo： 140-75-0

Molecular Formula： C₇H₈FN

Appearance： Colorless to light yellow liquid

Best Quality Chinese Manufacturer Supply 4-fluorobenzylamine 140-75-0 Cheapest Price

Molecular Formula:C7H8FN
Molecular Weight:125.146
Appearance/Colour:Colorless to light yellow liquid
Vapor Pressure:0.134mmHg at 25°C
Melting Point:183 °C
Refractive Index:n20/D 1.512(lit.)
Boiling Point:184.3 °C at 760 mmHg
PKA:9.01±0.10(Predicted)
Flash Point:73.3 °C
PSA：26.02000
Density:1.101 g/cm³
LogP:1.98470

4-Fluorobenzylamine(Cas 140-75-0) Usage

Chemical Properties	Colorless to light yellow liquid.
Uses	4-Fluorobenzylamine is used as a potassium channel blocking agent. It is used in the synthesis of new tris-iron(III) chelates of 3-hydroxy-4-pyridinone ligands. It reacts with the α- and γ-carboxyl groups of folic acid to yield 18F-labeled folate2. It is an important building block for the synthesis of 18F-labeled compounds.
General Description	[18F]4-fluorobenzylamine reacts with the α- and γ-carboxyl groups of folic acid to yield 18F-labeled folate. It is an important building block for the synthesis of 18F-labeled compounds.
Synthesis	In a 100ml reaction flask, add 25.5g (0.1mol) of N-(4-fluorobenzyl)phthalimide and 25ml of absolute ethanol, then add 6.3g (0.1mol) of 80% hydrazine hydrate solution, and heat Reflux 0.5g. Excessive hydrochloric acid was added to decompose the precipitated white precipitate, after cooling, an appropriate amount of water was added to stir, and suction filtered. The filtrate was neutralized with NaOH solution, extracted with ether, and the ether extract was dried, evaporated to remove ether, distilled under reduced pressure, and collected fractions at 44-46°C (67kPa) to obtain 7.1 g of 4-fluorobenzylamine, with a yield of 56.5%.

InChI:InChI=1/C7H3F2NS/c8-5-1-2-7(10-4-11)6(9)3-5/h1-3H

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140-75-0 Process route

: 459-57-4
4-fluorobenzaldehyde

: 459-56-3
4-fluorobenzylic alcohol

: 932724-63-5
tris(4-fluorobenzyl)amine

: 140-75-0
para-fluorobenzylamine

: 100-46-9
benzylamine

: 134227-41-1
1-(4-fluorophenyl)-N-[(4-fluorophenyl)methyl]methanamine

Conditions

Conditions	Yield
With ammonia; hydrogen; Ni/C catalyst; In water; at 120 ℃; for 17.5h; under 28502.9 - 33753.4 Torr;	90.7% 0.4% 1.2% 1.8% 1.4%

: 318-49-0
2-(4-fluorobenzyl)isoindoline-1,3-dione

: 612-14-6
phthalyl alcohol

: 140-75-0
para-fluorobenzylamine

Conditions

Conditions	Yield
With [Ru(P^tBuNNH^tBu)H(CO)Cl]; potassium tert-butylate; hydrogen; In tetrahydrofuran; at 110 ℃; for 24h; under 15001.5 Torr; Autoclave;
With C₂₅H₁₉BrMnN₂O₂P; potassium tert-butylate; hydrogen; In tetrahydrofuran; at 130 ℃; for 48h; under 22502.3 Torr; Inert atmosphere; Glovebox; Autoclave; Green chemistry;	84 %Spectr. 89 %Spectr.