100986-89-8

  • Product Name:Levofloxacin carboxylic acid
  • Molecular Formula:C13H9F2NO4
  • Purity:99%
  • Molecular Weight:281.216
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Product Details;

CasNo: 100986-89-8

Molecular Formula: C13H9F2NO4

Export Buy Reliable Quality Levofloxacin carboxylic acid 100986-89-8 Lowest Price

  • Molecular Formula:C13H9F2NO4
  • Molecular Weight:281.216
  • Vapor Pressure:3.14E-09mmHg at 25°C 
  • Melting Point:>280 °C 
  • Refractive Index:1.635 
  • Boiling Point:459.2 °C at 760 mmHg 
  • PKA:4.87±0.40(Predicted) 
  • Flash Point:231.5 °C 
  • PSA:68.53000 
  • Density:1.61 g/cm3 
  • LogP:1.93130 

Levofloxacin carboxylic acid(Cas 100986-89-8) Usage

Chemical Properties

White Solid

Uses

Levofloxacin intermediate.

InChI:InChI=1/C13H9F2NO4/c1-5-4-20-12-9(15)8(14)2-6-10(12)16(5)3-7(11(6)17)13(18)19/h2-3,5H,4H2,1H3,(H,18,19)/t5-/m0/s1

100986-89-8 Relevant articles

Novel ofloxacin derivatives: Synthesis, antimycobacterial and toxicological evaluation

Dinakaran, Murugesan,Senthilkumar, Palaniappan,Yogeeswari, Perumal,China, Arnab,Nagaraja, Valakunja,Sriram, Dharmarajan

, p. 1229 - 1236 (2008)

Thirty novel 9-fluoro-2,3-dihydro-8,10-(...

Preparation method of levofloxacin intermediate

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Paragraph 0017; 0042-0056, (2020/09/16)

The invention relates to a preparation m...

Synthesis method of levofloxacin carboxylic acid (by machine translation)

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Paragraph 0037-0045, (2020/02/27)

The method comprises the following steps...

ANTIBIOTIC RESISTANCE BREAKERS

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Page/Page column 77; 78, (2019/01/05)

The invention relates to antibiotic comp...

Environment-friendly method for preparing levofloxacin hydrochloride

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Paragraph 0019; 0023; 0027, (2017/10/05)

The invention provides an environment-fr...

100986-89-8 Process route

ethyl (S)-(-)-9,10-Difluoro-3-Methyl-7-Oxo-2,3-Dihydro-7H-Pyrido[1,2,3-de]-[1,4]Benzoxazine-6-Carboxylate
106939-34-8

ethyl (S)-(-)-9,10-Difluoro-3-Methyl-7-Oxo-2,3-Dihydro-7H-Pyrido[1,2,3-de]-[1,4]Benzoxazine-6-Carboxylate

levofloxacin Q-acid
100986-89-8

levofloxacin Q-acid

Conditions
Conditions Yield
With hydrogenchloride; acetic acid;
91%
In hydrogenchloride; acetic acid; for 0.666667h; Heating;
61%
With hydrogenchloride; acetic acid;
 
With hydrogenchloride; water; In acetic acid; at 75 - 80 ℃; for 6h;
 
With hydrogenchloride; In acetic acid;
 
With sulfuric acid; acetic acid; In water; for 4h; Time; Reflux;
 
With sulfuric acid; acetic acid; In N,N-dimethyl-formamide; for 1h; Time; Reflux; Green chemistry;
4.81 g
With sulfuric acid; acetic acid; In water; at 20 ℃; for 3h; Temperature; Reflux;
 
With sulfuric acid; acetic acid; In N,N-dimethyl-formamide; for 1h; Reflux;
 
With water; sodium hydroxide; In ethanol; at 20 ℃; for 1h;
 
ethyl (S)-(-)-9,10-Difluoro-3-Methyl-7-Oxo-2,3-Dihydro-7H-Pyrido[1,2,3-de]-[1,4]Benzoxazine-6-Carboxylate; With water; sodium carbonate; at 98.5 ℃; for 5h; Inert atmosphere; Large scale;
pH=4; Temperature; Reagent/catalyst; Acidic conditions; Large scale;
5.12 kg
C<sub>14</sub>H<sub>11</sub>F<sub>2</sub>NO<sub>4</sub>

C14H11F2NO4

levofloxacin Q-acid
100986-89-8

levofloxacin Q-acid

Conditions
Conditions Yield
With hydrogenchloride; acetic acid; In water; for 12h;
95.9%

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