16133-25-8
- Product Name：Pyridine-3-sulfonyl chloride
- Molecular Formula：C5H4ClNO2S
- Purity：99%
- Molecular Weight：177.611
Product Details;
CasNo： 16133-25-8
Molecular Formula： C5H4ClNO2S
Buy Quality Pyridine-3-sulfonyl chloride 16133-25-8 Offer with Lowest Price
- Molecular Formula:C5H4ClNO2S
- Molecular Weight:177.611
- Melting Point:144 °C
- Boiling Point:284.162 °C at 760 mmHg
- PKA:-1.77±0.11(Predicted)
- Flash Point:125.657 °C
- PSA：55.41000
- Density:1.489 g/cm3
- LogP:2.08990
16133-25-8 Relevant articles
Regioselective Lithiation of 3-Pyridylsulfonic Acid Derivatives: A Convenient Route to Various New 4-Substituted 3-Pyridylsulfonamides
Breant, P.,Marsais, F.,Queguiner, G.
, p. 822 - 824 (1983)
-
Synthesis and biological evaluation of N-(7-indolyl)-3-pyridinesulfonamide derivatives as potent antitumor agents.
Owa, Takashi,Yoshino, Hiroshi,Okauchi, Tatsuo,Okabe, Tadashi,Ozawa, Yoichi,Hata Sugi, Naoko,Yoshimatsu, Kentaro,Nagasu, Takeshi,Koyanagi, Nozomu,Kitoh, Kyosuke
, p. 2097 - 2100 (2002)
We herein report the synthesis and antit...
Synthetic method of pyridine-3-sulfonyl chloride
-
Paragraph 0028-0032, (2021/05/26)
The invention provides a synthetic metho...
SUBSTITUTED QUINOLINES AND METHODS FOR TREATING CANCER
-
Paragraph 0310, (2018/05/24)
Substituted quinoline compounds, methods...
Environment-friendly chemical synthetic method for 3-pyridine sulfonyl chloride
-
Paragraph 0090, (2017/04/03)
The invention provides an environment-fr...
Systematic variation of the benzenesulfonamide part of the GluN2A selective NMDA receptor antagonist TCN-201
Müller, Sebastian L.,Schreiber, Julian A.,Schepmann, Dirk,Strutz-Seebohm, Nathalie,Seebohm, Guiscard,Wünsch, Bernhard
supporting information, p. 124 - 134 (2017/02/23)
GluN2A subunit containing N-methyl-D-asp...
16133-25-8 Process route
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- 16133-25-8
Pyridine-3-sulfonyl chloride
-
- 7087-68-5
N-ethyl-N,N-diisopropylamine
Conditions
| Conditions | Yield |
|---|---|
|
|
-
- 636-73-7
3-pyridinesulfonic acid
-
- 16133-25-8
Pyridine-3-sulfonyl chloride
Conditions
| Conditions | Yield |
|---|---|
|
With phosphorus pentachloride; In trichlorophosphate; at 120 ℃; for 12h;
|
98% |
|
With phosphorus pentachloride; trichlorophosphate; for 3h; Heating / reflux;
|
94% |
|
With phosphorus pentachloride; In toluene; Heating;
|
92% |
|
With phosphorus pentachloride; trichlorophosphate; for 8h; Reflux;
|
90% |
|
With thionyl chloride; N,N-dimethyl-formamide; at 25 - 80 ℃; for 12h; Inert atmosphere;
|
89.6% |
|
With phosphorus pentachloride; trichlorophosphate; at 20 - 110 ℃; for 17h; Heating / reflux;
|
88% |
|
3-pyridinesulfonic acid; With phosphorus pentachloride; trichlorophosphate; at 20 - 110 ℃; for 17h; Heating / reflux;
With sodium hydrogencarbonate; In dichloromethane; water; pH=7;
|
88% |
|
With phosphorus pentachloride; In chlorobenzene; at 105 ℃; for 3h; Solvent;
|
87.9% |
|
With phosphorus pentachloride; In trichlorophosphate; at 120 ℃;
|
85% |
|
With phosphorus pentachloride; In chlorobenzene; at 119 - 122 ℃; Solvent; Temperature;
|
83.9% |
|
With phosphorus pentachloride; In trichlorophosphate; for 4h; Reflux;
|
75% |
|
With phosphorus pentachloride; trichlorophosphate; for 3h; Heating;
|
72% |
|
With phosphorus pentachloride; at 130 ℃; for 20h;
|
66% |
|
With phosphorus pentachloride; at 135 ℃; for 2.5h;
|
64% |
|
With phosphorus pentachloride; at 120 ℃;
|
|
|
With phosphorus pentachloride; for 3h; Heating;
|
|
|
With phosphorus pentachloride; trichlorophosphate; at 120 ℃; for 12h;
|
|
|
With phosphorus pentachloride; at 110 ℃; for 3h;
|
|
|
With phosphorus pentachloride; trichlorophosphate; at 120 - 130 ℃;
|
|
|
With phosphorus pentachloride;
|
|
|
With phosphorus pentachloride; In toluene;
|
30.7 g (92%) |
|
With phosphorus pentachloride; In toluene;
|
|
|
With phosphorus pentachloride; trichlorophosphate;
|
|
|
With phosphorus pentachloride;
|
|
|
With phosphorus pentachloride; trichlorophosphate; at 120 ℃; for 12h;
|
|
|
With phosphorus pentachloride; In trichlorophosphate; for 3h; Reflux; Inert atmosphere;
|
|
|
With phosphorus pentachloride; trichlorophosphate; at 130 ℃; for 3h; Inert atmosphere;
|
|
|
With hydrogenchloride; phosphorus pentachloride; trichlorophosphate; at 120 ℃;
|
|
|
With phosphorus pentachloride; In toluene; for 16h; Reflux;
|
0.70 g |
|
With thionyl chloride; N,N-dimethyl-formamide; at 75 ℃; for 1.5h;
|
|
|
With phosphorus pentachloride; trichlorophosphate; at 120 ℃; for 4h; Inert atmosphere;
|
16133-25-8 Upstream products
-
626-55-1
3-Bromopyridine
-
636-73-7
3-pyridinesulfonic acid
-
16133-26-9
pyridine-3-thiol
-
42899-76-3
pyridine-3-sulfonyl chloride hydrochloride
16133-25-8 Downstream products
-
873407-32-0
N-(2-pyridyl)-3-pyridylsulfonamide
-
111664-38-1
pyridine-3-sulfonic acid-[3-(6-ethoxy-[2]quinolyl)-anilide]
-
88842-76-6
pyridine-3-sulfonic acid-(3-benzo[f]quinolin-3-yl-anilide)
-
88842-77-7
pyridine-3-sulfonic acid-(4-benzo[f]quinolin-3-yl-anilide)
Relevant Products
-
Clopidogrel hydrogen sulfateCAS：135046-48-9
-
Betahistine dihydrochlorideCAS：5579-84-0
-
TicargrelorCAS：274693-27-5
