72235-52-0

  • Product Name:2,4-Difluorobenzylamine
  • Molecular Formula:C7H7F2N
  • Purity:99%
  • Molecular Weight:143.136
Inquiry

Product Details;

CasNo: 72235-52-0

Molecular Formula: C7H7F2N

Appearance: clear colorless to light yellow liquid

Factory Sells Buy Quality 2,4-Difluorobenzylamine 72235-52-0 Cheap Price

  • Molecular Formula:C7H7F2N
  • Molecular Weight:143.136
  • Appearance/Colour:clear colorless to light yellow liquid 
  • Vapor Pressure:1.02mmHg at 25°C 
  • Melting Point:255-256 °C(Solv: N,N-dimethylformamide (68-12-2)) 
  • Refractive Index:n20/D 1.49(lit.)  
  • Boiling Point:177.8 °C at 760 mmHg 
  • PKA:8.58±0.10(Predicted) 
  • Flash Point:68.3 °C 
  • PSA:26.02000 
  • Density:1.214 g/cm3 
  • LogP:2.12380 

2,4-Difluorobenzylamine(Cas 72235-52-0) Usage

Chemical Properties

clear colorless to light yellow liquid

Uses

2,4-Difluorobenzylamine has been used in the synthesis of βAla–Aib(N-fluoroarylmethyl)], nonpolar nucleobase dipeptide via Ugi four-component condensation reaction.

InChI:InChI=1/C7H7F2N/c8-6-2-1-5(4-10)7(9)3-6/h1-3H,4,10H2/p+1

72235-52-0 Relevant articles

PROCESS FOR PREPARATION OF HALOGENATED BENZYLAMINE AND INTERMEDIATES THEROF

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Page/Page column 18; 20-21, (2020/08/13)

The present invention provides an improv...

Hydrogen Bond Directed Photocatalytic Hydrodefluorination and Methods of Use Thereof

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, (2021/01/22)

Methods of synthesizing compounds compri...

Novel route for preparing dolutegravir key intermediate 2,4-difluorobenzylamine

-

, (2018/11/22)

The invention discloses a production rou...

2. 4 - difluorobenzene methylamine synthetic method

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Paragraph 0069-0071, (2017/10/22)

The invention relates to the fields of m...

72235-52-0 Process route

2,4-difluorobenzonitrile
3939-09-1,103496-86-2

2,4-difluorobenzonitrile

2,4-Difluoro-benzylamine
72235-52-0

2,4-Difluoro-benzylamine

Conditions
Conditions Yield
With ammonium hydroxide; hydrogen; In water; isopropyl alcohol; at 60 - 80 ℃; under 7500.75 Torr; Temperature; Reagent/catalyst;
90%
With [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; 1,4-di(diphenylphosphino)-butane; iso-butanol; sodium hydroxide; at 120 ℃; for 0.333333h; Inert atmosphere;
75 %Chromat.
C<sub>13</sub>H<sub>17</sub>F<sub>2</sub>N<sub>4</sub><sup>(1+)</sup>*Br<sup>(1-)</sup>

C13H17F2N4(1+)*Br(1-)

2,4-Difluoro-benzylamine
72235-52-0

2,4-Difluoro-benzylamine

Conditions
Conditions Yield
With hydrogenchloride; In methanol; water; for 6h; Reflux;
90.8%

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