881674-56-2
- Product Name：5-(2-fluorophenyl)-1H-Pyrrole-3-carboxaldehyde
- Molecular Formula：C11H8FNO
- Purity：99%
- Molecular Weight：189.189
Product Details;
CasNo： 881674-56-2
Molecular Formula： C11H8FNO
Quality Factory Supply High Purity 5-(2-fluorophenyl)-1H-Pyrrole-3-carboxaldehyde 881674-56-2 with Safe Delivery
- Molecular Formula:C11H8FNO
- Molecular Weight:189.189
- Melting Point:133 °C
- Boiling Point:370.6±32.0 °C(Predicted)
- PKA:14.77±0.50(Predicted)
- PSA：32.86000
- Density:1.270±0.06 g/cm3(Predicted)
- LogP:2.63330
881674-56-2 Relevant articles
Preparation method 5 - (2 - fluorophenyl) - 1H - pyrrole -3 - formaldehyde
-
Paragraph 0072-0089, (2021/11/19)
The invention belongs to the technical f...
Synthesis method of 5-(2-fluorophenyl)-1H-pyrrole-3-formaldehyde
-
, (2021/01/20)
The invention discloses a synthetic meth...
Preparation method of fumaric acid Vonoprazan intermediate
-
Paragraph 0061-0085, (2021/07/28)
The invention relates to a preparation m...
Preparation method 5 - (2 - fluorophenyl) - 1H - pyrrole -3 - formaldehyde
-
Paragraph 0079-0100, (2021/10/20)
The invention provides a preparation met...
881674-56-2 Process route
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- 1240948-77-9
5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile
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- 881674-56-2
5-(2-fluorophenyl)-1H-pyrrole-3-carboxaldehyde
| Conditions | Yield |
|---|---|
|
With hydrogen; acetic acid; In tetrahydrofuran; water; at 20 - 30 ℃; for 5h; Inert atmosphere;
|
90.54% |
|
With hydrogen; acetic acid; In tetrahydrofuran; water; at 15 - 25 ℃; for 4h; Reagent/catalyst; Temperature;
|
84.4% |
|
With pyridine; hydrogen; acetic acid; In water; at 30 ℃; for 20h; Temperature; Reagent/catalyst; Industrial scale;
|
84.9% |
|
5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile; With hydrogen; acetic acid; Raney-nickel; In tetrahydrofuran; water; at 15 - 25 ℃; for 3h;
With water; sodium hydroxide; In tetrahydrofuran; ethyl acetate; at 10 - 35 ℃; pH=7 - 8;
With hydrogenchloride; water; In tetrahydrofuran; ethyl acetate; at 15 - 25 ℃; pH=3 - 3.5;
|
78% |
|
5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile; With hydrogen; acetic acid; In tetrahydrofuran; at 20 ℃; for 3h;
With water; sodium hydroxide; at 20 ℃; pH=7 - 8;
|
76.9% |
|
With formic acid; water; hydrogen; In tetrahydrofuran; for 2.5h; under 750.075 Torr;
|
51.5% |
|
With hydrogen; acetic acid; In tetrahydrofuran; water; at 20 ℃; for 2h;
|
42% |
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- 881674-58-4
(5-(2-fluorophenyl)-1H-pyrrol-3-yl)methanol
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- 881674-56-2
5-(2-fluorophenyl)-1H-pyrrole-3-carboxaldehyde
| Conditions | Yield |
|---|---|
|
With sodium bromate; sulfuric acid; bromine; sodium bromide; In dichloromethane; water; butan-1-ol; at 0 - 5 ℃; for 3.5h; Solvent;
|
95.1% |
|
With [bis(acetoxy)iodo]benzene; In dichloromethane; at 20 ℃; for 12h;
|
92% |
|
With tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide; In acetonitrile; at 20 ℃; for 1.5h;
|
60% |
|
With 4-methylmorpholine N-oxide; tetrapropylammonium perruthennate; In acetonitrile; at 20 ℃; for 1.5h;
|
|
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With tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide; In acetonitrile; at 20 ℃; for 1.5h; Molecular sieve;
|
881674-56-2 Upstream products
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881674-58-4
(5-(2-fluorophenyl)-1H-pyrrol-3-yl)methanol
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114615-82-6
tetrapropylammonium perruthennate
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881674-06-2
5-(2-fluorophenyl)-1H-pyrrole-3-carboxylic acid ethyl ester
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1240948-72-4
2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile
881674-56-2 Downstream products
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928324-56-5
4-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde
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928324-57-6
4-fluoro-5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde
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928324-91-8
5-(2-fluorophenyl)-4-iodo-1H-pyrrole-3-carbaldehyde
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881677-09-4
5-(2-fluorophenyl)-1-[(2-fluorophenyl)sulfonyl]-1H-pyrrole-3-carbaldehyde
Relevant Products
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1,2,3-Trifluoro-4-nitrobenzeneCAS：771-69-7
-
2-METHYLRESORCINOLCAS：608-25-3
-
2-Chloro-5-(2-fluorophenyl)-1h-pyrrole-3-carbonitrileCAS：1240948-72-4
